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Tzu-Hsuen Yuan

Tzu-Hsuen YuanImage

Name

Yuan, Tzu-Hsuen

Title

Associate Professor

Current Position

Associate Professor in Department of Health and Welfare, College of City Management, University of Taipei

Degree

Doctor of Philosophy in Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University

Experiences

Project Assistant Professor in Institute of Environmental

  and Occupational Health Sciences, College of Public

  Health, National Taiwan University

Visiting Researcher in University of Tsukuba, Japan

Visiting Researcher in National Institute for

  Environmental Studies, Japan

Post-Doctoral Fellow in Institute of Occupational  

  Medicine and Industrial Hygiene, College of Public

  Health, National Taiwan University

Expertise

Environmental and Occupational Epidemiology、Biomonitoring、Heavy Metal Analysis、Air Pollution、Injury Epidemiology
Courses

Epidemiology、Global Health、Drug Control and Food Health、Health Detection and Analysis

E-mail

thyuan@utaipei.edu.tw; jamesfisher955@gmail.com

Office phone number

02-2871-8288#4052

Research Projects

期刊/Publications
  1. Yuan TH, Tai CJ, Tsai CH, Chien JW, Eguchi A, Li CY, Lin CW, Mori C, Chan CC. Exploring the influence of PCB exposure on neonatal birth outcomes and neurobehavioral development after 15 years of prohibition. Environ Pollut. 2025;368:125761.
  2. Chen CS, Yuan TH, Lu TP, Lee HY, Chen YH, Lai LC, Tsai MH, Chuang EY, Chan CC. Exposure associated DNA methylation among people exposed to multiple industrial pollutants. Clinical Epigenetics 2024;16(1):111.
  3. Laiman V, Chuang HC, Lo YC, Yuan TH, Chen YY, Heriyanto DS, Yuliani FS, Chung KF, Chang JH. Cigarette smoke-induced dysbiosis: comparative analysis of lung and intestinal microbiomes in COPD mice and patients. Respir Res 2024;25(1):204.
  4. Lin WC, Shie RH, Yuan TH, Tseng CH, Chiang CJ, Lee WC, Chan CC. A nationwide case-referent study on elevated risks of adenocarcinoma lung cancer by long-term PM2.5 exposure in Taiwan since 1997. Environ Res 2024;252:118889.
  5. Laiman V, Lo YC, Chen HC, Yuan TH, Hsiao TC, Chen JK, Chang CW, Lin TC, Li SJ, Chen YY, Heriyanto DS, Chung KF, Chuang KJ, Ho KF, Chang JH, Chuang HC. Data on lung and intestinal microbiome after air pollution exposure in ageing rats. Data Brief 2023;47:109004.
  6. Manullang A, Chung CL, Lee YL, Yuan TH, Tran HM, Makrufardi F, Chung KF, Lee KY, Chang JH, Chuang HC. COPD with Eosinophilic Inflammation is Susceptible to Particulate Air Pollution Exposure. Aerosol Air Qual Res 2023;23: 230035.
  7. Tsai LJ, Yuan TH, Shie RH, Chiang CH, Chan CC. Association between ambient air pollution exposure and insomnia among adults in Taipei City. Scientific Reports 2022;12:19064.
  8. Laiman V, Lo YC, Chen HC, Yuan TH, Hsiao TC, Chen JK, Ching-Wen Chang CW, Lin TC, Li SJ, Chen YY, Heriyanto DS, Chung KF, Chuang KJ, Ho KF, Chang JH, Chuang HC. Effects of antibiotics and metals on lung and intestinal microbiome dysbiosis after sub-chronic lower-level exposure of air pollution in ageing rats. Ecotoxicology and Environmental Safety 2022;246:114164.
  9. Lee NW, Wang HY, Du CL, Yuan TH, Chen CY, Yu CJ, Chan CC. Air-polluted environmental heavy metal exposure increase lung cancer incidence and mortality: A population-based longitudinal cohort study. Sci Total Environ 2022;810:152186. <SCI>
  10. Yuan TH, Eguchi A, Tai CJ, Tsai CH, Chien JW, Chan CC, Mori C. Comparison of the PCB serum levels among mother-child pairs in areas of Eastern Japan and Central Taiwan. Sci Total Environ 2022;806:150272. <SCI>
  11. Yuan TH, Yu MT, Ikenaka Y, Chen YH, Nakayama SF, Chan CC. Characteristics of neonicotinoid and metabolite residues in Taiwanese tea leaves. J Sci Food Agric 2022; 102(1):341-349. <SCI>
  12. Chiang CT, Hwang YH, Su CC, Tsai KY, Lian IeB, Yuan TH, Chang TK. Elucidating the underlying causes of oral cancer through spatial clustering in high-risk areas of Taiwan with a distinct gender ratio of incidence. Geospat Health 2010;4(2):230-242. <SCI>
  13. Hwang YH, Chen YH, Su YN, Hsu CC, Chen YH, Yuan TH. Genetic polymorphism of As3MT and delayed urinary DMA excretion after organic arsenic intake from oyster ingestion. J Environ Monit 2010;12(6):1247-1254. <SCI>
  14. Chiang CT, Chang TK, Hwang YH, Su CC, Tsai KY, Yuan TH, Lian IB. A critical exploration of blood and environmental chromium concentration among oral cancer patients in an oral cancer prevalent area of Taiwan. Environ Geochem Health 2011;33(5): 469-476.<SCI>
  15. Yuan TH, Lian IB, Tsai KY, Chang TK, Chiang CT, Su CC, Hwang YH. Possible association between nickel and chromium and oral cancer: a case-control study in central Taiwan. Sci Total Environ 2011;409(6):1046-1052. <SCI>
  16. Shie RH, Yuan TH, Chan CC. Using pollution roses to assess sulfur dioxide impacts in a township downwind of a petrochemical complex. J Air Waste Manag Assoc 2013;63(6):702-711. <SCI>
  17. Chio CP, Yuan TH, Shie RH, Chan CC. Assessing vanadium and arsenic exposure of people living near a petrochemical complex with two-stage dispersion models. J Hazard Mater 2014;271:98-107.<SCI>
  18. Chuang HC, Juan HT, Chang CN, Yan YH, Yuan TH, Wang JS, Chen HC, Hwang YH, Lee CH, Cheng TJ. Cardiopulmonary toxicity of pulmonary exposure to occupationally relevant zinc oxide nanoparticles. Nanotoxicology 2014;8(6):593-604. <SCI>
  19. Yuan TH, Shie RH, Chin YY, Chan CC. Assessment of the levels of urinary 1-hydroxypyrene and air polycyclic aromatic hydrocarbon in PM 2.5 for adult exposure to the petrochemical complex emissions. Environ Res 2015;136, 219-226. <SCI>
  20. Yuan TH, Chung MK, Lin CY, Chen ST, Wu KY, Chan CC. Metabolic profiling of residents living in the vicinity of a petrochemical complex. Sci Total Environ 2016;548-549: 260-269. <SCI>
  21. Yuan TH, Chio CP, Shie RH, Pien WH, Chan CC. The distance-to-source trend in vanadium and arsenic exposures for residents living near a petrochemical complex. Journal of Exposure Science and Environmental Epidemiology 2016;26(3): 270-276 <SCI>
  22. Chan YJ, Yuan TH, Sun HC, Lin TC. Characterization and exposure assessment of odor emissions from laser cutting of plastics in the optical film industry. Aerosol and Air Quality Research 2016;16(9): 2216–2226. <SCI>
  23. Yang TH, Yuan TH, Hwang YH, Lian IB, Meng MH, Su CC. Increased inflammation in rheumatoid arthritis patients living where farm soils contain high levels of copper. J Formos Med Assoc 2016; 115(11):991-996<SCI>
  24. Chiang TY, Yuan TH, Shie RH, Chen CF, Chan CC. Increased incidence of allergic rhinitis, bronchitis and asthma, in children living near a petrochemical complex with SO2 pollution. Environ International 2016;96:1-7 <SCI>
  25. Chen CS, Yuan TH, Shie RH, Wu KY, Chan CC. Linking sources to early effects by profiling urine metabolome of residents living near oil refineries and coal-fired power plants. Environ International 2017;102:87-96. <SCI>
  26. Chan YJ, Yuan TH, Tsai YH, Lin TC. Characterization of Endocrine Disruptors and Particulate Matter Emissions from Laser Cutting of Plastic Film in the TFT-LCD Industry. Aerosol and Air Quality Research 2017;17:1539-1549 <SCI>
  27. Yuan TH, Shen YC, Shie RH, Chan CC. Increased cancers among residents living in the neighborhood of a petrochemical complex: a 12-year retrospective cohort study. Int J Hyg Environ Health 2018;221(2):308-314. <SCI>
  28. Chen CF, Chio CP, Yuan TH, Yeh YP, Chan CC. Increased cancer incidence of Changhua residents living in Taisi Village north to the No. 6 Naphtha Cracking Complex. Journal of the Formosan Medical Association 2018, pii: S0929-6646(17)30731-3. doi: 10.1016/j.jfma.2017.12.013. <SCI>
  29. Chuang HC, Shie RH, Chio CP, Yuan TH, Lee JH, Chan CC. Cluster analysis of fine particulate matter (PM2.5) emissions and its bioreactivity in the vicinity of a petrochemical complex. Environmental Pollution 2018;236:591-597. <SCI>
  30. Chen CS, Kuo TC, Kuo HC, Tseng YJ, Kuo CH, Yuan TH, Chan CC. Metabolomics of Children and Adolescents Exposed to Industrial Carcinogenic Pollutants. Environ Sci Technol. 2019;53(9):5454-5465. <SCI>
  31. Yuan TH, Ke DY, Wang EH, Chan CC. Associations between renal functions and exposure of arsenic and polycyclic aromatic hydrocarbon in adults living near a petrochemical complex. Environmental Pollution 2020;256:113457 <SCI>
  32. 詹馥妤, 詹長權, 李睿桓, 袁子軒, 施淑芳, 陳政友, 胡益進. 台北市社區空氣汙染與皮膚老化之關係. 台灣衛誌2020年第39卷第2期:p143-154.
  33. Killian B, Yuan TH, Tsai CH, Tina H. T. Chiu, Chen YH, Chan CC. Emission-related heavy metal associated with oxidative stress in children: effect of antioxidant intake. Int J Environ Res Public Health 2020;17:3920. <SCI>
  34. Yuan TH, Chen JL, Shie RH, Yeh YP, Chen YH, Chan CC. Liver fibrosis associated with potential vinyl chloride and ethylene dichloride exposure from the petrochemical industry. Sci Total Environ 2020;739:139920. <SCI>
  35. Chuang HC, Shie RH, Lee CH, Chio CP, Yuan TH, Lee JH, Chan CC. Associations of soluble metals and lung and liver toxicity in mice induced by fine particulate matter originating from a petrochemical complex. Environ Sci Pollut Res 2020;27(27):34442-34452. <SCI>
  36. Shun CH, Yuan TH*, Hung SH, Yeh YP, Chen YH, Chan CC. Assessment of the hyperlipidemia risk for residents exposed to potential emitted metals in the vicinity of a petrochemical complex. Environ Sci Pollut Res 2021;28:27966–27975. <SCI>
  37. Yuan TH, Jhuang MJ, Yeh YP, Chen YH, Lu S, Chan CC. The relationship between renal function and metal exposure of residents living in north to the No. 6 Naphtha Cracking Complex. J Formos Med Assoc 2021 (Article in Press) <SCI>
  38. Yuan TH, Yu MT, Ikenaka Y, Chen YH, Nakayama SF, Chan CC. Characteristics of neonicotinoid and metabolite residues in Taiwanese tea leaves. J Sci Food Agric 2021; DOI 10.1002/jsfa.11363 <SCI>
  39. Chen CH, Kuo TC, Kuo HC, Tseng YJ, Kuo CH, Yuan TH, Chan CC. Lipidomics of children and adolescents exposed to multiple industrial pollutants. Environ Res 2021;201:111448. <SCI>

研討會論文/conference papers
  1. Yuan TH, Li CY, Chan CC. Evaluating Environmental Policy Effectiveness by Urinary Heavy Metal Levels and Biochemical Indicators of Residents near a Petrochemical Complex in Taiwan. Joint Annual Meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology 2025, Atlanta, USA, August 17-20, 2025.
  2. Yuan TH, Chang CY, Shie RH, Chan CC. To explore the heat injury news events by short- and long-term trends of heat indexes in Taiwan. The International Society for Environmental Epidemiology Asia and Western Pacific Chapter & International Society of Exposure Science Asia Chapter Joint Conference 2024, Kota Kinabalu, Malaysia, June 23-26, 2024.
  3. Yuan TH, Shie RH, Lu JY, Chang CY. The impact on air pollution by epidemic prevention policy of COVID-19 in Taipei of Taiwan. 35th Annual Conference of the International Society for Environmental Epidemiology, Kaohsiung, Taiwan, October 17-21, 2023.
  4. Yuan TH, Wu PC, Lee JH, Wu C, Chan CC. Temporal and spatial distribution of PM2.5 pollution in Taipei City and its association with traffic flows assessed by microsensor data. 34rd Annual Conference of the International Society for Environmental Epidemiology, Athens, Greece, September 18-21, 2022.
  5. Yuan TH, Shih BT, Chen CH, Chan CC. The Exposure of Mercury Species in Blood Cell and the Effects on Metabolites of Residents Living Near Coal-Fired Power Plants. 33rd Annual Conference of the International Society for Environmental Epidemiology, online conference, August 23-26, 2021.
  6. Yuan TH, Hsieh YT, Chan CC. Inorganic arsenic exposure of children residents living near the petrochemical complex. Conference of the International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter 2019, Daegu, Korea, October 17-19, 2019.
  7. Yuan TH, Eguchi A, Tai CJ, Tsai CH, Chien JW, Chan CC, Mori C. The comparison on PCBs exposure levels in birth cohorts between Taiwan and Japan. 39th International Symposium on Halogenated Persistent Organic Pollutants, Kyoto, Japan, August 25-30, 2019.
  8. Yuan TH, Jhuang MJ , Shun CH , Chio CP, Yeh YP, Chan CC. Association between Urinary Metal Levels and Chronic Kidney Disease in Residents Living Near to a Big Petrochemical Complex. 30th Conference of the International Society for Environmental Epidemiology, Ottawa, Canada, August 26-30, 2018.
  9. Yuan TH, Chen CH, Chiang TY, Killian B, Chan CC. The exposomics approach to explore children's health effects in the vicinity of a petrochemical complex. Conference of the International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter 2018, Taipei, Taiwan, June, 21-25, 2018.
  10. Yuan TH, Shun CH, Chan CC. Hyperlipidemia of Adults Living in the Vicinity of a Petrochemical Complex. 29th Conference of the International Society for Environmental Epidemiology, Sydney, Australia, September 24-28, 2017.
  11. Yuan TH, Shun CH, Chan CC. Serum heavy metal levels of residents in the vicinity of a petrochemical complex in Taiwan. 18th International Conference on Heavy Metals in the Environment, Ghent, Belgium, September 12-15, 2016.
  12. Yuan TH, Ke DY, Chan CC. Study on renal functions among adult residents in the vicinity of a petrochemical complex. 28th Conference of the International Society for Environmental Epidemiology, Rome, Italy, September 1-4, 2016.
  13. Yuan TH, Chan CC. Health effects of residents in the vicinity of a petrochemical complex in central Taiwan. Conference of International Society for Environmental Epidemiology and International Society of Exposure Science-Asia Chapter 2016, Sapporo, Japan, June 26-29, 2016.
  14. Yuan TH, Chan CC. Early biomarkers of non-communicable diseases for residents in the vicinity of a petrochemical complex. APRU-2015 Global Health Workshop, Osaka, Japan, October 30-November 1, 2015.
  15. Yuan TH, Shen YC, Chan CC. Study on cancer incidence among adult residents in the vicinity of a petrochemical complex since its operation. 27th Conference of the International Society for Environmental Epidemiology, Sao Paulo, Brasil, August 30-September 3, 2015.
  16. Yuan TH, Lin CY, Chen ST, Wu KY, Chan CC. Early effects markers for residents exposed to metals and PAHs in the vicinity of a petrochemical complex. 27th Conference of the International Society for Environmental Epidemiology, Sao Paulo, Brasil, August 30-September 3, 2015.
  17. Yuan TH. Health and biological markers for residents in the vicinity of a petrochemical complex. 2015 International Conference on Industrial Hygiene and Occupational Medicine, Kaohsiung, Taiwan, April 25-26, 2015.
  18. Yuan TH, Shie RH, Chin YY, Chan CC. The distance-to-source trend in urinary 1-hydroxypyrene levels among adults living near a petrochemical complex. Conference of ISEE, ISES and ISIAQ, Basel, Switzerland, August 19-23, 2013.
  19. Yuan TH, Pien WH, Shie RH, Chan CC. Exposure Assessment of Long-term Air Pollution in the Vicinity of a Petrochemical Complex in Taiwan. 22nd Annual Meeting of the International Society of Exposure Science, Seattle, Washington, October 28-November 1, 2012.
  20. Yuan TH, Pien WH, Chan CC. Urinary heavy metal levels of residents in the vicinity of a petrochemical complex in Taiwan. 16th International Conference on Heavy Metals in the Environment, Rome, Italy, September 23-27, 2012.
  21. Yuan TH, Lian IB, Tsai KY, Chang TK, Chiang CT, Su CC, Hwang YH. Effects of matrix metalloproteinase-2 and -9 with metals on oral cancer. 2011 International Conference of Industrial Hygiene and Occupational Health, Taichung, Taiwan, April 23-24, 2011.
  22. Yuan TH, Lian IB, Tsai KY, Chang TK, Chiang CT, Su CC, Hwang YH. Possible association of nickel and chromium with oral cancer: a case-control study in central Taiwan. 15th International Conference on Heavy Metals in the Environment, Gdańsk, Poland, September 19-23, 2010.
  23. 袁子軒：台灣環境重金屬與健康效應之探討。2010海峽兩岸博士生環境論壇，北京，中國，October 29-30，2010。
  24. Yuan TH. Effects of chromium and nickel exposure on oral cancer in Changhua, Taiwan. The 21st International Conference on Epidemiology in Occupational Health, Taipei, Taiwan, April 21-25, 2010.
  25. Yuan TH, Hwang YH, Chu WT. Use of portable X-ray fluorescence (PXRF) in monitoring arsenic exposure during the preventive mai Hygiene ntenance task in the microelectronic industry. 2006 American Industrial Conference and Expo, Chicago, Illinois, May 13-18, 2006.

Research Projects
  1. 以氣象及疾病因素為中介變項去探討懸浮微粒與交通事故發生風險及傷害程度之關聯性研究：以六都為例，國科會，計畫主持人，2025/8/1~2027/7/31
  2. 114年建立化學物質特性資訊公開資料，瑞昶科技股份有限公司，協同主持人，2025/4/10~2025/12/31
  3. 某石化工業區風險管理措施對周邊社區空氣品質及人群健康改善之研究--某石化工業區風險管理措施對周邊居民空氣汙染暴露相關生物指標與急慢性疾病衝擊之研究，國科會，計畫主持人，2024/8/1~2025/10/31
  4. 112 年度因應氣候變遷之農地資源空間調適策略研析，農委會，共同主持人，2023/3/18~2023/12/31
  5. 建立化學物質特性資訊之公開資料，瑞昶科技股份有限公司，協同主持人，2023/2/24～2023/11/30
  6. 新冠肺炎流行病學資料整理，工研院，計畫主持人，2022/11/01~ 2023/04/30
  7. 111 年度因應氣候變遷之農地資源空間調適策略研析，農委會，共同主持人，2022/05/21~2022/12/31
  8. 「艾卡爾新冠病毒檢測計畫」之流行病學研究計畫，富佳生技股份有限公司，計畫主持人，2022/01/01~2022/06/30
  9. 建置我國化學物質之毒理資料庫，瑞昶科技股份有限公司，共同主持人，2021/07/01~2022/11/30
  10. 台灣空氣汙染與肺癌之環境流行病學研究，科技部，共同主持人，2021/08/01~2022/07/31
  11. 奈米微粒暴露對勞工健康風險評估，勞研所，共同主持人，2021/04/29-2021/12/10
  12. 空氣汙染長期暴露對於慢性腎臟疾病、肺癌和大腸直腸癌之相關性研究，國衛院，協同主持人，2021/01/01-2024/12/31
  13. Risk assessment of pollutants by omics approaches in people living near No. 6 Naphtha Cracking Plant, National Health Research Institutes, Co-Principal Investigator, 2019/01/01~2021/12/31
  14. Integrating the internet of things (IoT): Air Quality Effect on Public Health Impact Assessment from 2018 to 2019, National Science and Technology Center for Disaster Reduction, Co-Principal Investigator, 2018/05/01~2019/05/31
  15. PM2.5 environmental and health education study in Taipei in 2018, Environmental Protection Bureau in Taipei City, Co-Principal Investigator, 2018/04/25~2018/12/31
  16. Influence of food residue antibiotics on intestinal flora and human health, Ministry of Science and Technology, Co-Principal Investigator, 2017/05/01~2020/04/30
  17. Evidence-based risk management assessment and communication for the food safety system: from epidemiology to health policy, Ministry of Science and Technology, Co-Principal Investigator, 2017/05/01~2019/04/30
  18. Personal Information Law and Big Data Project: Social Needs, Public Interests and Personal Data Protection, Ministry of Science and Technology, Co-Principal Investigator, 2016/08/01~2019/07/31
  19. Assessment the impact of polychlorinated biphenyls exposure on birth cohort in the vicinity of industrial areas in central Taiwan, Ministry of Science and Technology, Principal Investigator, 2017/08/01~2018/07/31
  20. The environmental epidemiologic study in the vicinity of an incinerator near the Shen-Mei Pond, Environmental Protection Bureau in Taoyuan City, Principal Investigator, 2016/09/08~2017/09/07
  21. Environmental epidemiological cohort study in Yunlin County (2016-2017), Public Health Bureau in Yunlin County, Principal Investigator, 2016/04/01~2017/3/31
  22. Environmental epidemiological study in Dacheng Township of Changhua County, Public Health Bureau in Changhua County, Co-Principal Investigator, 2015/08/18~2016/10/31
  23. Study on metal exposure and toxicity in the vicinity of No.6 Naphtha Cracking Complex, Ministry of Science and Technology, Principal Investigator, 2015/08/01~2018/07/31
  24. Exposomics research on common complex diseases (3/3), National Taiwan University, Post-Doctoral Fellow, 2015/04/01~2015/07/31
  25. Environmental epidemiological cohort study in Yunlin County (2015-2016), Public Health Bureau in Yunlin County, Post-Doctoral Fellow, 2015/03/10~2016/3/10
  26. Environmental epidemiological cohort study in Yunlin County (2013-2014), Public Health Bureau in Yunlin County, Post-Doctoral Fellow, 2013/09/01~2014/12/31
  27. Exposomics research on common complex diseases (1/3), National Taiwan University, Post-Doctoral Fellow, 2013/07/20~2013/12/31
  28. Air pollution and health among residents near a petrochemical complex in Yunlin County: a cohort study (2012-2013), Environmental Protection Bureau in Yunlin County, Post-Doctoral Fellow, 2012/07/20~2013/07/19
  29. Air pollution and health among residents near a petrochemical complex in Yunlin County: a cohort study (2011-2012), Environmental Protection Bureau in Yunlin County, Post-Doctoral Fellow, 2012/02/01~2012/07/19
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